Medical Bioengineering SectionBiomaterials Engineering
Preparation of Highly-oriented Polycrystalline Ceramics Composed of Ion-substituted Hydroxyapatite
In order to develop novel ceramics-based biomaterials that can replace the functions of tissues, influences of the structure and chemical composition of apatite ceramics on biocompatibility are clarified.
■ Preparation of partially ion-substituted hydroxyapatite
Oxo-acid ion-substituted apatite ceramics are prepared to control their lattice structures, since disorder of the lattice structure of hydroxyapatite influences its biodegradability and adsorption behaviors of cellular growth factors.
■ Preparation of highly-oriented polycrystalline oxide ceramics
To mimic the surface structure of the tooth enamel, nanorod arrays of hydroxyapatite crystals having preferred orientation are prepared by soaking calcium-containing silicate glass substrates in alkaline phosphate solutions.
■ Synthesis using interfacial interactions between functional molecules and bioceramics
Functionalization of hydroxyapatite is achieved by the interfacial organic/inorganic interaction between functional molecules and hydroxyapatite.

Faculty
Medical Bioengineering Section Biomaterials Engineering